Radiation damping compensation of selective pulses in water-protein exchange spectroscopy

The observation of nuclear Overhauser effects (NOEs) between bound water and biol. macromols. such as proteins and nucleic acids can be improved by inverting the water resonance selectively while compensating for radiation damping effects. The efficiency of inversion, the offset profiles, and the appearance of 2D NOE-NOESY spectra can be improved in comparison with earlier methods. [on SciFinder (R)]

Published in:
Journal of Biomolecular NMR, 17, 4, 323-330
Year:
2000
Laboratories: