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research article
Normalized one-dimensional NOE measurements in isotopically labeled macromolecules using two-way cross-polarization
A novel one-dimensional NOE expt. is presented where a selected proton is excited by two-way heteronuclear cross-polarization between protons and nitrogen-15 or carbon-13. The utility of the method is demonstrated for a sample of 15N labeled human ubiquitin. Inter- and intra-residue NOEs are clearly obsd. in a very time-effective manner. The signal intensities can be easily normalized. [on SciFinder (R)]
Type
research article
Authors
Chiarparin, Elisabetta
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Cutting, Brian
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Eykyn, Thomas R.
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Publication date
1999
Published in
Volume
13
Issue
1
Start page
61
End page
65
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
February 22, 2006
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