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research article
Enantiomerically pure 7-oxabicyclo[2.2.1]hept-5-en-2-yl derivatives ("Naked sugars") as synthetic intermediates. Part XXII. Stereoselective synthesis of (1R)-1-C-(6-amino-7H-purin-8-yl)-1,4-anhydro-2,3-dideoxy-3-fluoro-D-erythro-pentitol
1992
The "naked sugar" (+)-(1R,2S,4R)-2-cyano-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl (1S)-camphanate [(+)-3] (Diels-Alder adduct of furan with 1-cyanovinyl (1S)-camphanate) was converted into (1R)-1-C-(6-amino-7H-purin-8-yl)-1,4-anhydro-2,3-dideoxy-3-fluoro-D-eryt hro-pentitol [(+)-2] in nine synthetic steps and 12% overall yield.
Type
research article
Authors
Publication date
1992
Published in
Issue
8
Start page
676
End page
678
Peer reviewed
REVIEWED
Available on Infoscience
February 21, 2006
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