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research article
New synthetic route toward polyketide-like macrolides
2006
New pathways toward the synthesis of polyketide-like macrolides have been developed through the functionalization of long chain polyolic fragments readily obtained from 3,3'-methylenebis{[6-(benzyloxy)methoxy]cyclohept-3-en-1-ol} derivatives 6. This synthetic route generates a large variety of stereoisomers and thus can be applied to the preparation of a library of polyhydroxylated macrocycles, analogues of natural bioactive macrolides.
Type
research article
Web of Science ID
WOS:000236253600004
Publication date
2006
Published in
Issue
5
Start page
685
End page
688
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
February 16, 2006
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