The invention relates to a novel class of ligands, complexes comprising such ligands and a metal ion, and adducts of these metal complexes and a macromolecule. Pharmaceutical compositions and methods of making and using the ligand-metal complexes are also described. The invention also relates to the use of macromolecular adducts for enhancement of diagnostic imaging. In particular, the invention relates to (ethylene)-(propylene)-triaminepentaacetic acid (EPTPA) derivatives, a process for their production, and their use for the production of pharmaceutical agents for NMR diagnosis or radiodiagnosis or radiotherapy.
Titre
Preparation of (ethylene)-(propylene)-triaminepentaacetic acid derivatives for use in the production of pharmaceutical agents
Date
2003
Note
Alternative title(s) :
(de) (ethylene)-(propylene)-triaminopentaessigsäure derivate, verfahren zu ihrer herstellung und ihre verwendung in der herstellung pharmazeutischer wirkstoffe
(fr) Derives d'acide ethylene propylene triamino-pentaacetique, un procede de production correspondant, et leur utilisation dans la production d'agents pharmaceutiques
(en) (ethylene)-(propylene)-triaminepentaacetic acid derivatives, process for their production, and their use for the production of pharmaceutical agents
Autres identifiant(s)
EPO Family ID: 56290306
Date de création de la notice
2006-02-15
