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research article
Synthesis of biotinylated glycosulfopeptides by chemoselective ligation
2001
Tyrosine sulfation and O-glycosylation are two post-translational modifications playing an essential role in modulation of biol. activity, protein folding and cellular communication. Here, a novel chem. approach for the synthesis of biotinylated glycosulfopeptides is described based on a combination of acid labile protecting groups, highly acid sensitive resins and two orthogonal chemoselective ligation reactions. [on SciFinder (R)]
Type
research article
Authors
Publication date
2001
Published in
Volume
42
Issue
12
Start page
2297
End page
2299
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
February 9, 2006
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