Pseudoproline libraries for tuning inhibitors of SH3 domain mediated protein-protein interactions
Fernandez-Carneado, Jimena; Durieux, Patricia; Patiny, Luc; Tatsu, Yoshiro; Grell, Daniel; Kardinal, Christian; Feller, Stephan; Tuchscherer, Gabriele
2001

Résumé

A symposium report. Pseudoprolines such as Ser, Thr, Cys derived proline-ring structures with enhanced inherent properties of L-Pro were used to evaluate ligand receptor interaction of Pro-rich peptides. The generation of pseudoproline-libraries exhibiting enhanced proline properties allows for rapid screening of a large no. of proline-rich peptides in the search of potent inhibitors of Src homol. (SH3)-mediated interactions. [on SciFinder (R)]

Détails

Titre Pseudoproline libraries for tuning inhibitors of SH3 domain mediated protein-protein interactions
Auteur(s) Fernandez-Carneado, Jimena ; Durieux, Patricia ; Patiny, Luc ; Tatsu, Yoshiro ; Grell, Daniel ; Kardinal, Christian ; Feller, Stephan ; Tuchscherer, Gabriele
Publié dans Peptides: The Wave of the Future, Proceedings of the Second International and the Seventeenth American Peptide Symposium, San Diego, CA, United States, June 9-14, 2001
Pages 185-186
Date 2001
Laboratoires LCBP
Le document apparaît dans Production scientifique et compétences > SB - Faculté des sciences de base > SB Archives > LCBP - Laboratoire de chimie biomimétique et des peptides
Publications validées par des pairs
Papiers de conférence
Travail produit à l'EPFL
Publié
Date de création de la notice 2006-02-09

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