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research article
Template-Assembled Synthetic Proteins (TASP). Cyclic Templates with Incorporated Turn-Inducing Mimics
The 8-amino-5,6,7,8-tetrahydronaphth-2-oic acid (1), 8-(aminomethyl)-5,6,7,8-tetrahydronaphth-2-oic acid (2), and 8-(aminomethyl)naphth-2-oic acid (3) were synthesized in their protected forms as turn-inducing dipeptide mimics.Two of them (2 and 3) were incorporated into a novel type of cyclic, peptide-based structures (see 21 and 34-36) designed as templates for the synthesis of TASP molecules.
Type
research article
Authors
Earnest, Ivan
•
Kalvoda, Jaroslav
•
Francotte, Eric
•
Rihs, Grety
•
Fritz, Hans
•
Blommers, Marcel J. J.
•
Raschdorf, Fritz
•
Sigel, Christoph
•
Mutter, Manfred
Publication date
1993
Published in
Volume
76
Issue
4
Start page
1539
End page
1563
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
February 9, 2006
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