Template-Assembled Synthetic Proteins (TASP). Cyclic Templates with Incorporated Turn-Inducing Mimics
1993
Abstract
The 8-amino-5,6,7,8-tetrahydronaphth-2-oic acid (1), 8-(aminomethyl)-5,6,7,8-tetrahydronaphth-2-oic acid (2), and 8-(aminomethyl)naphth-2-oic acid (3) were synthesized in their protected forms as turn-inducing dipeptide mimics.Two of them (2 and 3) were incorporated into a novel type of cyclic, peptide-based structures (see 21 and 34-36) designed as templates for the synthesis of TASP molecules.
Details
Title
Template-Assembled Synthetic Proteins (TASP). Cyclic Templates with Incorporated Turn-Inducing Mimics
Author(s)
Earnest, Ivan ; Kalvoda, Jaroslav ; Francotte, Eric ; Rihs, Grety ; Fritz, Hans ; Blommers, Marcel J. J. ; Raschdorf, Fritz ; Sigel, Christoph ; Mutter, Manfred
Published in
Helvetica Chimica Acta
Volume
76
Issue
4
Pages
1539-1563
Date
1993
ISSN
0018-019X
Other identifier(s)
DOI: https://doi.org/10.1002/hlca.19930760414
Laboratories
LCBP
Record Appears in
Scientific production and competences > SB - School of Basic Sciences > SB Archives > LCBP - Laboratory of biomimetic and peptide chemistry
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Peer-reviewed publications
Work produced at EPFL
Journal Articles
Published
Record creation date
2006-02-09