TEMPLATE-ASSEMBLED SYNTHETIC PROTEINS (TASP) - CYCLIC TEMPLATES WITH INCORPORATED TURN-INDUCING MIMICS

The 8-amino-5,6,7,8-tetrahydronaphth-2-oic acid (1), 8-(aminomethyl)-5,6,7,8-tetrahydronaphth-2-oic acid (2), and 8-(aminomethyl)naphth-2-oic acid (3) were synthesized in their protected forms as turn-inducing dipeptide mimics.Two of them (2 and 3) were incorporated into a novel type of cyclic, peptide-based structures (see 21 and 34-36) designed as templates for the synthesis of TASP molecules.


Published in:
Helv. Chim. Acta, 76, 4, 1539-1563
Year:
1993
ISSN:
0018-019X
Laboratories:




 Record created 2006-02-09, last modified 2018-12-03


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