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research article
Switch Peptides: pH‐Induced α‐Helix to β‐Sheet Transitions of Bis‐amphiphilic Oligopeptides
The interconversion of two secondary structure types (alpha-helix reversible beta-sheet) induced by external conditions such as pH, temperature, concentration, and solvent could be proved in a new class of amphiphilic peptides (switch peptides) in aqueous solution. The pH-dependent conformational changes were studied by CD spectroscopy. Special attention was given to the investigations of four newly synthesized peptides with similar sequences.
Type
research article
Authors
Publication date
1991
Published in
Volume
30
Issue
11
Start page
1514
End page
1516
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
February 9, 2006
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