In this article, we introduce the approach to the realization of ontogenetic development and fault tolerance that will be implemented in the POEtic tissue, a novel reconfigurable digital circuit dedicated to the realization of bio-inspired systems. The modelization in electronic hardware of the developmental process of multi-cellular biological organisms is an approach that could become extremely useful in the implementation of highly complex systems, where concepts such as self-organization and fault tolerance are key issues. The concepts presented in this article represent an attempt at finding a useful set of mechanisms to allow the implementation in digital hardware of a bio-inspired developmental process with a reasonable overhead.