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research article
Deracemization of 5-(4-hydroxyphenyl)-5-phenylhydantoin (HPPH): practical synthesis of (-)-(S)-HPPH
In the presence of 10% NaOH in boiling MeOH enantiomerically enriched HPPH is racemized. This permits the deracemization of HPPH in the presence of brucine, giving enantiomerically pure (-)-(S)-HPPH [(-)-(S)-5-(4-hydroxyphenyl)-5-phenylhydandoin]. (C) 2004 Elsevier Ltd. All rights reserved.
Type
research article
Web of Science ID
WOS:000224017700012
Authors
Publication date
2004
Published in
Volume
15
Issue
17
Start page
2657
End page
2660
Note
Swiss Fed Inst Technol, Lab Glycochim & Synth Asymet, CH-1015 Lausanne, Switzerland.
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
November 9, 2005
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