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research article
Resolution of 7-oxabicyclo[2.2.1]hept-5-en-2-one via cyclic aminals
High yielding resolution of racemic 7-oxabicyclo[2.2.1]hept-5-en-2-one (+/-)-1 ('7-oxanorbornenone') via aminal formation with (R,R)-1,2-diphenylethylenediamine 2 is reported. Ac idle hydrolysis furnishes the enantiomeric ketones (+)-1 and (-)-1 (greater than or equal to 95% ee). The chiral diamine is efficiently recovered. (C) 1999 Elsevier Science Ltd. All rights reserved.
Type
research article
Authors
Publication date
1999
Published in
Volume
10
Issue
3
Start page
567
End page
571
Note
Univ Fribourg, Inst Chim Organ, CH-1700 Fribourg, Switzerland. Univ Lausanne, Inst Chim Organ, CH-1015 Lausanne, Switzerland.
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
November 9, 2005
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