The effects of different working gases on the transition from linear ohmic confinement (LOC) regime to saturated ohmic confinement (SOC) regime and its relation to the intrinsic toroidal rotation reversal phenomenon were explored in the TCV tokamak. The energy confinement saturation was studied across D, H and He density ramps, and a range of ECRH injection power and through variations of ohmic plasma current. The occurrence of rotation reversal, concomitantly with the LOC-SOC transition, was observed only for certain cases, making us formally exclude a causal relation between the two phenomena. A strong correlation between the evolution of toroidal rotation profiles and electron density gradients was, however, observed, in agreement with previous works (Lebschy et al 2017 Nucl. Fusion 58 026013; Hornsby et al 2018 Nucl. Fusion 58 056008). Linear gyrokinetic simulations were performed to probe the turbulent regime of these discharges, showing a dominance of trapped electron mode (TEM) during the LOC phase and a mixture of TEM and ion temperature gradient (ITG) following the transition to SOC regime in D. Such a TEM/ITG bifurcation was less pronounced in H and He. MHD activity was monitored throughout the discharges and possible correlations between sawteeth instability activity, energy confinement time saturation and rotation reversal are highlighted.