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  4. Automated Detection Of Highly Aggregated Neurons In Microscopic Images Of Macaque Brain
 
conference paper

Automated Detection Of Highly Aggregated Neurons In Microscopic Images Of Macaque Brain

You, Zhenzhen
•
Jiang, Ming  
•
Shi, Zhenghao
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January 1, 2020
2020 Ieee International Conference On Image Processing (Icip)
IEEE International Conference on Image Processing (ICIP)

Neuron detection is a key step in individualizing and counting neurons which are important for assessing physiological and pathophysiological information. A large number of methods including deep learning networks have been proposed but mainly targeting regions with few aggregated neurons. The objective of this paper is to address an automated neuron detection problem in heterogeneous hippocampus region with different degrees of neuron aggregation. Since deep learning networks require a lot of ground truths hut neuron instance annotation is impossible in regions where numerous neurons are clustered, ground truth of centroids marked at the center of neurons is created for training. We propose a multiscale convolutional neural network (CNN) to regress neuron centroid mapping across image. Using multiscale information makes the proposed network applicable not only for single individual neurons, but also for a large number of aggregated neurons. Experimental results show that our method is superior to state-of-the-art deep learning -based algorithms. To our knowledge, this is the first deep learning study to detect neurons in regions of highly clustered neurons.

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Type
conference paper
DOI
10.1109/ICIP40778.2020.9190747
Web of Science ID

WOS:000646178500063

Author(s)
You, Zhenzhen
Jiang, Ming  
Shi, Zhenghao
Shi, Cheng
Du, Shuangli
Liang, Jimin
Herard, Anne-Sophie
Jan, Caroline
Souedet, Nicolas
Delzescaux, Thierry
Date Issued

2020-01-01

Publisher

IEEE

Publisher place

New York

Published in
2020 Ieee International Conference On Image Processing (Icip)
ISBN of the book

978-1-7281-6395-6

Series title/Series vol.

IEEE International Conference on Image Processing ICIP

Start page

315

End page

319

Subjects

Imaging Science & Photographic Technology

•

neuron detection

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point annotation

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multiscale cnn

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hippocampus region

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microscopic image

•

total number

•

glial-cells

•

cortex

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LTS5  
Event nameEvent placeEvent date
IEEE International Conference on Image Processing (ICIP)

ELECTR NETWORK

Sep 25-28, 2020

Available on Infoscience
June 19, 2021
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/179213
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