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research article
Amino acid-based H2S donors: N-thiocarboxyanhydrides that release H2S with innocuous byproducts
May 6, 2021
A library of N-thiocarboxyanhydrides (NTAs) derived from natural amino acids with benign byproducts and controlled H2S-release kinetics is reported. Minimal acute in vitro toxicity was observed in multiple cell lines, while longer-term toxicity in cancer cells was observed, with slow-releasing donors exhibiting the greatest cytotoxic effects.
Type
research article
Web of Science ID
WOS:000647856500001
Authors
•
Enders, Patrick
•
Zhu, Yumeng
•
Bratton, Abigail F.
•
Powell, Chadwick R.
•
Kashfi, Khosrow
•
Matson, John B.
Publication date
2021-05-06
Published in
Volume
57
Start page
5522
End page
5525
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
May 22, 2021
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