research article
The spatial organization of cGAS-TREX1 interactions
April 5, 2021
Coupling DNA sensing to the initiation of immune responses necessitates auxiliary control mechanisms to avoid autoimmunity. A key factor is the exonuclease TREX1, which antagonizes DNA-mediated activation of cGAS. Two studies, by Mohr et al. (2021) and Zhou et al. (2021), uncover new aspects of this important control mechanism.
Type
research article
Web of Science ID
WOS:000641581300003
Author(s)
Date Issued
2021-04-05
Publisher
Published in
Volume
56
Issue
7
Start page
876
End page
877
Subjects
Editorial or Peer reviewed
REVIEWED
Written at
EPFL
EPFL units
Available on Infoscience
May 22, 2021
Use this identifier to reference this record