This thesis evaluates the effects of the position of the concrete core and its stiffness on the horizontal deformation of a multi-storey timber-concrete hybrid building. As part of the evaluation a calculation method with polynomial functions was derived to estimate the deformations of the highest slab due to a continuous horizontal surface load. The polynomial functions calculate the deformation in xand y-direction on each point of the slab and depend on the position of the concrete core, its stiffness and the amount of horizontal loading. This allows to estimate the deformations efficiently when designing a building. The effects of different concrete cores and positions were evaluated with the calculation method derived before. It was found that the position of the core further from the line of the resultant force yields higher deformations than a position on the line of the core. It was also found that the stiffness of the core has a significant effect on the deformation of the highest slab. The stiffness of the core was varied by different sizes of the core and different wall thicknesses. The result of the influences of these parameters were shown in a zone map, where the limits of the horizontal surface loads for each core position and stiffness are shown.