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research article
Palladium-Catalyzed Multicomponent Synthesis of Fully Substituted Alkylidene Furanones
September 4, 2020
In the presence of a catalytic amount of Pd(OAc)(2) and XantPhos, the three-component reaction of ynones, imines, and aryl iodides affords fully substituted alkylidene-furan-3(2H)-ones via a sequence of the Mannich reaction followed by chemo- and regioselective oxypalladation and reductive elimination. One carbon-oxygen and two carbon-carbon bonds are generated to afford the heterocycle in good to excellent yield.
Type
research article
Web of Science ID
WOS:000569377600065
Authors
Publication date
2020-09-04
Publisher
Published in
Volume
22
Issue
17
Start page
7030
End page
7033
Peer reviewed
REVIEWED
Available on Infoscience
October 1, 2020
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