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research article
Synthesis of Benzo[a]carbazoles through Visible Light-Induced Cycloaromatization
June 29, 2020
We report herein a synthesis of 5,6-diarylbenzo[a]carbazoles by a sequence of 6 pi-electrocyclization followed by beta-elimination. The highly functionalized 2,3-disubstituted indoles used for this cycloaromatization process are prepared by Pd-catalyzed cyclizative cross-coupling ofortho-alkynylanilines withortho-alkynylbenzamides. The combination of these two reactions allows us to develop a facile synthesis of benzo[a]carbazoles directly from two easily accessible internal alkynes without isolation of the indole intermediates.
Type
research article
Web of Science ID
WOS:000543806700001
Authors
Publication date
2020-06-29
Publisher
Published in
Volume
103
Issue
8
Article Number
e2000106
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
July 9, 2020
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