3D-Integration Of Printed Electrochemical Sensors In Pet Microfluidics For Biochemical Sensing

This paper presents a novel process for screen printed electrode fabrication, functionalization and integration in a polyethylene terephthalate (PET) fluidics system for electrochemical analysis. The innovative components utilized are: 1. 3D Through-Foil Vias (TFVs) for electrode connection, enabling simple liquid tight lamination of micro-fluidic channels; 2. Screen printed carbon and silver/silver chloride (Ag/AgCl) electrodes on 3D vias; and 3. PET fluidics with a fabrication process compatible with large-area manufacturing. A platform integrating an Ag/AgCl pseudo-reference and a glucose oxidase (GOx)-modified working electrode has been used for glucose sensing in the flexible fluidics system. Detection of small glucose concentrations between 100-400 mu M through Cyclic Voltammetry (CV) is shown. The sensor shows linear response and good sensitivity of similar to 0.8 mA/(mM cm(2)). By changing the electrode coatings, the same technology can potentially be used for detecting multiple analytes in biofluids.

Published in:
2019 20Th International Conference On Solid-State Sensors, Actuators And Microsystems & Eurosensors Xxxiii (Transducers & Eurosensors Xxxiii), 2464-2467
Presented at:
20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII (TRANSDUCERS and EUROSENSORS), Berlin, GERMANY, Jun 23-27, 2019
Jan 01 2019
New York, IEEE

 Record created 2020-07-09, last modified 2020-07-15

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