Loading...
research article
Activatable fluorescent probes for hydrolase enzymes based on coumarin-hemicyanine hybrid fluorophores with large Stokes shifts
May 25, 2020
We show that the equilibrium of intramolecular spirocyclization of coumarin-hemicyanine hybrid fluorophores can be finely tuned by means of chemical modifications. We used this scaffold to develop activatable fluorescent probes with large Stokes shifts for gamma-glutamyltranspeptidase and esterase.
Type
research article
Web of Science ID
WOS:000537974900005
Authors
Fujioka, Hiroyoshi
•
Uno, Shin-nosuke
•
Kamiya, Mako
•
Kojima, Ryosuke
•
•
Urano, Yasuteru
Publication date
2020-05-25
Publisher
Published in
Volume
56
Issue
42
Start page
5617
End page
5620
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
June 20, 2020
Use this identifier to reference this record