Optical frequency combs have the potential to become key building blocks of wavelength-division multiplexing (WDM) communication systems. The strictly equidistant narrow-band spectral lines of a frequency comb can serve either as carriers for parallel WDM transmission or as local-oscillator (LO) tones for parallel coherent reception. When it comes to highly scalable WDM transceivers with compact form factor, chip-sale comb sources are of particular interest, and recent experiments have demonstrated the viability of such devices for high-speed communications with line rates of tens of Tbit/s. However, the output power of chip-scale comb sources is generally lower than that of their conventional discrete-element counterparts, thus requiring additional amplifiers and impairing the optical signal-to-noise ratio (OSNR). In this paper, we investigate the influence of the power and optical carrier-to-noise ratio (OCNR) of the comb lines on the performance of the WDM link. We identify two distinctively different regimes, where the transmission performance is either limited by the comb source or by the link and the associated in-line amplifiers. We further investigate the impact of line-to-line power variations on the achievable OSNR and link capacity using a soliton Kerr frequency comb as a particularly interesting example. We believe that our findings will help to compare different comb generator types and to benchmark them with respect to the achievable transmission performance. (C) 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreement