Maldi device and methods of preparation and use thereof

A target plate for enhanced matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) analysis of intact biological entities. The target plate comprises an electrically conductive substrate (1) covered at least partially with immobilised photo-reactive nanoparticles (2), acting as a photosensitizer and an ionization device, which drives efficient electron-transfer and radical reactions causing in-source disruption of the envelope structure of intact biological entities (3) and helps in desorption/ionization of components such as lipids, peptides and proteins from the intact biological entities to the MS analyser.


Year:
2018
Keywords:
Note:
Alternative title(s) : (fr) Dispositif maldi et procédés de préparation et d'utilisation associés
Other identifiers:
EPO Family ID: 58462970
Laboratories:




 Record created 2019-12-05, last modified 2020-04-20


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