A PCM-based heat exchanger is disclosed, said phase change material (PCM)-based heat exchanger comprising: a) a case having insulated walls comprising an inlet and an outlet; and b) a plurality of modules comprising a support structure containing a phase change material, wherein said modules are arranged within said case in a way as to define a fluidic path connecting said inlet with said outlet. Another object relates to an apparatus, wherein said apparatus is an incubator, such as an infant incubator or a chicken/eggs incubator, or a glove box, characterized in that it comprises the PCM-based heat exchanger operatively connected with a hood defining an insulating compartment, a fan adapted for injecting an air flow into said PCM-based heat exchanger and a system to regulate the air temperature inside the hood.