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research article

Fully automated gridding reconstruction for non-Cartesian x-space magnetic particle imaging

Ozaslan, A. A.
•
Alacaoglu, A.  
•
Demirel, O. B.
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August 1, 2019
Physics In Medicine And Biology

Magnetic particle imaging (MPI) is a fast emerging biomedical imaging modality that exploits the nonlinear response of superparamagnetic iron oxide (SPIO) nanoparticles to image their spatial distribution. Previously, various scanning trajectories were analyzed for the system function reconstruction (SFR) approach, providing important insight regarding their image quality performances. While Cartesian trajectories remain the most popular choice for x-space-based reconstruction, recent work suggests that non-Cartesian trajectories such as the Lissajous trajectory may prove beneficial for improving image quality. In this work, we propose a generalized reconstruction scheme for x-space MPI that can be used in conjunction with any scanning trajectory. The proposed technique automatically tunes the reconstruction parameters from the scanning trajectory, and does not induce any additional blurring. To demonstrate the proposed technique, we utilize five different trajectories with varying density levels. Comparison to alternative reconstruction methods show significant improvement in image quality achieved by the proposed technique. Among the tested trajectories, the Lissajous and bidirectional Cartesian trajectories prove more favorable for x-space MPI, and the resolution of the images from these two trajectories can further be improved via deblurring. The proposed fully automated gridding reconstruction can be utilized with these trajectories to improve the image quality in x-space MPI.

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Type
research article
DOI
10.1088/1361-6560/ab3525
Web of Science ID

WOS:000482525700009

Author(s)
Ozaslan, A. A.
Alacaoglu, A.  
Demirel, O. B.
Cukur, T.
Saritas, E. U.
Date Issued

2019-08-01

Published in
Physics In Medicine And Biology
Volume

64

Issue

16

Article Number

165018

Subjects

Engineering, Biomedical

•

Radiology, Nuclear Medicine & Medical Imaging

•

Engineering

•

Radiology, Nuclear Medicine & Medical Imaging

•

magnetic particle imaging

•

image reconstruction

•

gridding reconstruction

•

non-cartesian trajectories

•

fourier inversion

•

relaxation

•

resolution

•

sensitivity

•

reduction

•

nmr

•

mpi

Editorial or Peer reviewed

REVIEWED

Written at

OTHER

EPFL units
LIONS  
Available on Infoscience
September 12, 2019
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/161094
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