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research article
Virology: Poxins Soothe the STING
May 6, 2019
The mammalian cyclic dinucleotide 2', 3'-cGAMP is a potent inducer of innate immune responses produced upon detection of cytosolic DNA by cGAS. The mechanisms underlying the control of intracellular cGAMP levels remained unclear. In a new study, Eaglesham et al. identified poxins as 2', 3'-cGAMP-specific nucleases allowing immune evasion by viruses.
Type
research article
Web of Science ID
WOS:000467138100013
Authors
Publication date
2019-05-06
Publisher
Published in
Volume
29
Issue
9
Start page
R332
End page
R334
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
June 18, 2019
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