Cryogenic Ion Spectroscopy for Identification of Monosaccharide Anomers

We combine conformer-selective, cryogenic infrared spectroscopy, quantum mechanical computations, and 18O substitution at the reducing end to determine the structural preferences of protonated glucosamine in the gas phase. Cryogenic infrared-infrared (IR-IR) double resonance spectroscopy of helium-tagged protonated glucosamine provides vibrational fingerprints of individual conformers, and 18O isotopic labeling facilitates the match with computed structures and provides a selective probe of the anomeric hydroxyl. This is key for using vibrational spectroscopy for glycan analysis and determining the generality of anomeric memory during glycosidic bond cleavage.


Publié dans:
The Journal of Physical Chemistry
Année
2019
Mots-clefs:
Autres identifiants:
Laboratoires:




 Notice créée le 2019-03-13, modifiée le 2019-03-31


Évaluer ce document:

Rate this document:
1
2
3
 
(Pas encore évalué)