One-step access to N-enoxyimides by gold-catalysed addition of N-hydroxyimides to terminal alkynes
N-Enoxyimides have become attractive substrates for novel catalytic transformations, yet their tedious multi-step synthesis hampers full exploitation of their synthetic potential. We report a gold(I)-catalyzed protocol to access N-enoxyimides from simple and widely available terminal alkynes and the corresponding N-hydroxyimides in a single step. The transformation proceeds with aryl-, alkenyl- and alkyl alkynes, facilitating further studies of this substrate class in C-H functionalizations and photocatalysis.
Manuscript-accepted.pdf
Postprint
openaccess
CC BY
557.09 KB
Adobe PDF
522971a9c00653105d42c1ea1eddc6d1
SI-enoxyimides-final.pdf
Postprint
openaccess
CC BY
3.1 MB
Adobe PDF
66e59722600818a7e817a984e77cbb09