Science is in revolution. The formidable scientific and technological developments of the last century have dramatically transformed the way in which we conduct scientific research. The knowledge and applications that science produces has profound consequences on our society, both at the global level (for example, climate change) and the individual level (for example, impact of mobile devices on our daily lives). These developments also have a profound impact on the way scientists are working today and will work in the future. In particular, informatics and mathematics have changed the way we deal with data, simulations, models and digital twins, publications, and importantly, also with ethics.