000263423 001__ 263423
000263423 005__ 20190619220155.0
000263423 022__ $$a0166-2236
000263423 022__ $$a1878-108X
000263423 02470 $$a000454424000007$$2isi
000263423 0247_ $$a10.1016/j.tins.2018.08.011$$2doi
000263423 037__ $$aARTICLE
000263423 245__ $$aNeural Circuits for Goal-Directed Sensorimotor Transformations
000263423 260__ $$c2019$$aLondon$$bELSEVIER SCIENCE LONDON
000263423 269__ $$a2019-01-01
000263423 336__ $$aReviews
000263423 520__ $$aPrecisely wired neuronal circuits process sensory information in a learning- and context-dependent manner in order to govern behavior. Simple sensory decision-making tasks in rodents are now beginning to reveal the contributions of distinct cell types and brain regions participating in the conversion of sensory information into learned goal-directed motor output. Task learning is accompanied by target specific routing of sensory information to specific downstream cortical regions, with higher-order cortical regions such as the posterior parietal cortex, medial prefrontal cortex, and hippocampus appearing to play important roles in learning- and context-dependent processing of sensory input. An important challenge for future research is to connect cell-type-specific activity in these brain regions with motor neurons responsible for action initiation.
000263423 650__ $$aNeurosciences
000263423 650__ $$aNeurosciences & Neurology
000263423 6531_ $$amedial prefrontal cortex
000263423 6531_ $$aposterior parietal cortex
000263423 6531_ $$avisual-cortex
000263423 6531_ $$amultisensory integration
000263423 6531_ $$aprojection neurons
000263423 6531_ $$afunctional specialization
000263423 6531_ $$aacetylcholine-release
000263423 6531_ $$adorsal hippocampus
000263423 6531_ $$areward seeking
000263423 6531_ $$abarrel cortex
000263423 700__ $$g165867$$0240842$$aCrochet, Sylvain
000263423 700__ $$aLee, Seung-Hee
000263423 700__ $$aPetersen, Carl C. H.$$0243169$$g157467
000263423 773__ $$k1$$j42$$q66-77$$tTrends In Neurosciences
000263423 8560_ $$fpierre.devaud@epfl.ch
000263423 909C0 $$meliane.blumer@epfl.ch$$0252149$$yApproved$$xU10837$$zBlumer, Eliane$$pLSENS
000263423 909CO $$preview$$ooai:infoscience.epfl.ch:263423$$pSV
000263423 961__ $$afantin.reichler@epfl.ch
000263423 973__ $$aEPFL$$sPUBLISHED$$rREVIEWED
000263423 980__ $$aREVIEW
000263423 980__ $$aWoS
000263423 981__ $$aoverwrite