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conference paper
Impact of MCT1 Haploinsufficiency on the Mouse Retina
January 1, 2018
Retinal Degenerative Diseases: Mechanisms And Experimental Therapy
The monocarboxylate transporter 1 (MCT1) is highly expressed in the outer retina, suggesting that it plays a critical role in photoreceptors. We examined MCT1+/- heterozygotes, which express half of the normal complement of MCT1. The MCT1(+/-) retina developed normally and retained normal function, indicating that MCT1 is expressed at sufficient levels to support outer retinal metabolism.
Use this identifier to reference this record
Type
conference paper
Web of Science ID
WOS:000443968600047
Authors
Peachey, Neal S.
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Yu, Minzhong
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Han, John Y. S.
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•
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Pellerin, Luc
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Philp, Nancy J.
Publication date
2018-01-01
Publisher
Published in
Retinal Degenerative Diseases: Mechanisms And Experimental Therapy
ISBN of the book
978-3-319-75402-4
978-3-319-75401-7
Publisher place
Cham
Series title/Series vol.
Advances in Experimental Medicine and Biology; 1074
Start page
375
End page
380
Peer reviewed
REVIEWED
EPFL units
Event name | Event place | Event date |
Kyoto, JAPAN | Sep 19-24, 2016 | |
Available on Infoscience
December 13, 2018