Raspberry-Pi based system for propofol monitoring

Induction of anesthesia with propofol is a largely adopted technique in hospital environments. The correct dosage of this compound is essential to avoid under- or over-anesthesia that may result in serious side-effects. Therefore, in clinical settings, long-term monitoring of propofol is of great importance. To this aim, in this work, we present the design and the validation of a custom-made, low-cost and portable Point-of-Care (PoC) system based on electrochemical detection for propofol monitoring. Fouling phenomenon due to phenolic oxidation of propofol has been overcome by adopting a Pencil Graphite Electrode (PGE) 3H as sensor. The validation of the system focused on testing the measurement speed through scan-rate analysis, which is important due to the fast clearance of propofol; and interference study with Paracetamol(APAP), since it is an analgesic compound frequently administered with propofol in medical practices.


Published in:
Integration-The Vlsi Journal, 63, 213-219
Year:
Sep 01 2018
Publisher:
Amsterdam, ELSEVIER SCIENCE BV
ISSN:
0167-9260
1872-7522
Keywords:
Laboratories:




 Record created 2018-12-13, last modified 2020-04-20


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