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research article
Inductively coupled plasma mass spectrometry to identify protein drug targets from whole cell systems
Proteins from cisplatin treated bacterial cells were partially separated by 1D polyacrylamide gel electrophoresis and analysed by laser ablation inductively coupled plasma mass spectrometry; using peptide fingerprinting methods central to proteomics, the band containing the highest levels of platinum was found to contain outer membrane protein A, which may be involved in cisplatin uptake
Type
research article
Authors
•
•
Abou-Shakra, Fadi R.
•
Birtwistleb, Heather
•
Coffey, Jonathan
Publication date
2001
Published in
Volume
1
Issue
24
Start page
2708
End page
2709
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
October 29, 2018
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