Loading...
research article
Improving the Thermodynamic Profiles of Potential Suzuki-Miyaura Cross-Coupling Catalysts by Altering the Electrophilic Coupling Component
2018
As a heavily used technique for forming new C-C bonds, developing new catalysts and reaction conditions for Suzuki-Miyaura cross-coupling reactions is desirable. Here, using volcano plots, the influence of the electrophilic coupling component in catalytic cycle thermodynamics is revealed. Less reactive electrophiles, such as iodine, broaden the volcano plateau resulting in more catalysts having “ideally balanced” thermodynamic profiles, than, for example, fluorine. This may represent an appealing strategy for developing new cross-coupling catalytic systems.
Type
research article
Authors
Publication date
2018
Published in
Volume
10
Start page
1
End page
10
Peer reviewed
REVIEWED
EPFL units
Funder | Grant Number |
FNS-NCCR | NCCR MARVEL |
Available on Infoscience
December 13, 2017
Use this identifier to reference this record