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  4. Irradiation in a flash: Unique sparing of memory in mice after whole brain irradiation with dose rates above 100 Gy/s
 
conference paper

Irradiation in a flash: Unique sparing of memory in mice after whole brain irradiation with dose rates above 100 Gy/s

Montay-Gruel, Pierre
•
Petersson, Kristoffer
•
Jaccard, Maud
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2017
Radiotherapy And Oncology
15th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology

This study shows for the first time that normal brain tissue toxicities after WBI can be reduced with increased dose rate. Spatial memory is preserved after WBI with mean dose rates above 100 Gy/s, whereas 10 Gy WBI at a conventional radiotherapy dose rate (0.1 Gy/s) totally impairs spatial memory. (C) 2017 Elsevier B.V. All rights reserved.

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Type
conference paper
DOI
10.1016/j.radonc.2017.05.003
Web of Science ID

WOS:000413383700004

Author(s)
Montay-Gruel, Pierre
Petersson, Kristoffer
Jaccard, Maud
Boivin, Gael
Germond, Jean-Francois
Petit, Benoit
Doenlen, Raphael
Favaudon, Vincent
Bochud, Francois
Bailat, Claude
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Date Issued

2017

Publisher

Elsevier Ireland Ltd

Publisher place

Clare

Published in
Radiotherapy And Oncology
Total of pages

5

Volume

124

Issue

3

Start page

365

End page

369

Subjects

Flash-RT

•

Whole brain irradiation

•

Cognition's preservation

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
SV  
Event nameEvent placeEvent date
15th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology

SWITZERLAND

JUN 17-19, 2017

Available on Infoscience
November 8, 2017
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/142068
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