Irradiation in a flash: Unique sparing of memory in mice after whole brain irradiation with dose rates above 100 Gy/s

This study shows for the first time that normal brain tissue toxicities after WBI can be reduced with increased dose rate. Spatial memory is preserved after WBI with mean dose rates above 100 Gy/s, whereas 10 Gy WBI at a conventional radiotherapy dose rate (0.1 Gy/s) totally impairs spatial memory. (C) 2017 Elsevier B.V. All rights reserved.


Published in:
Radiotherapy And Oncology, 124, 3, 365-369
Presented at:
15th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology, SWITZERLAND, JUN 17-19, 2017
Year:
2017
Publisher:
Clare, Elsevier Ireland Ltd
ISSN:
0167-8140
Keywords:
Laboratories:




 Record created 2017-11-08, last modified 2019-12-05


Rate this document:

Rate this document:
1
2
3
 
(Not yet reviewed)