Gold-catalyzed domino cyclization-alkynylation reactions with EBX reagents: new insights into the reaction mechanism

Gold-catalyzed domino processes constitute a useful alternative to C-H functionalization for the synthesis of functionalized (hetero)arenes. Herein, we report computational studies on the gold-catalyzed cyclization alkynylation of keto-allenes with ethynylbenziodoxole (EBX) reagents, which identified a gold(I) picolinate complex as the active catalyst, giving the first mechanistic insights into this transformation.


Published in:
Dalton Transactions, 46, 36, 12257-12262
Year:
2017
ISSN:
1477-9226
Laboratories:


Note: The file is under embargo until: 2018-09-06


 Record created 2017-10-09, last modified 2018-12-03

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