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research article
Role of SEC62 in ER maintenance: A link with ER stress tolerance in SEC62-overexpressing tumors?
Amplification of the candidate oncogene TLOC1/SEC62 in tumors correlates with reduced patient survival. The recently reported role of SEC62 as an autophagy receptor that controls endoplasmic reticulum (ER) size and function might open new scenarios for understanding the phenotypes and treat SEC62high tumors, which are characterized by high ER stress tolerance.
Type
research article
Web of Science ID
WOS:000406843600012
Authors
Bergmann, Timothy J.
•
Fumagalli, Fiorenza
•
Loi, Marisa
•
Molinari, Maurizio
Publication date
2017
Publisher
Published in
Volume
4
Issue
2
Article Number
e1264351
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
September 5, 2017
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