Detection and investigation of biological molecules by fourier transform infra-red spectroscopy
Method and apparatus to study biological molecules or biological components at or in self-assembled monolayers (SAMs) on metal surfaces (2) such as gold in aqueous environments (6) using attenuated total internal reflection Fourier transform infra-red (ATR-FTIR) spectroscopy are described. Said method may be used for e.g. the screening for effective substances suitable as agonists or antagonists or - if performed time resolved - for studying kinetics of interactions of e.g. biological molecules adsorption and desorption processes or for the development of materials and surfaces for biological or medical applications.
11004593
Alternative title(s) : (de) Detektion und untersuchung biologischer moleküle mit hilfe der infrarot-fouriertransformationsspektroskopie (fr) Detection et investigation de molecules biologiques par spectroscopie a infrarouge et transformees de fourier
TTO:6.0040
Patent number | Country code | Kind code | Date issued |
EP1002226 | EP | A1 | 2000-05-24 |
AU3356597 | AU | A | 1999-02-16 |
WO9905509 | WO | A1 | 1999-02-04 |