This paper will present an annual simulation-based workflow for assessing human perceptual and non-visual responses to daylight across a series of view positions in an architectural case study. Through the integration of mathematical models used to predict visual interest and non-visual health potential, this paper will introduce an automated workflow to assess an array of view positions (located at eye level) under varied sky conditions and across multiple view directions to analyze the predicted impacts of daylight on perception and health in architecture. This approach allows for a spatial and occupant centric analysis of daylight using an integrated simulation-based approach.