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research article
Antiproliferative activity of ruthenium and osmium clusters with phosphine ligands
New ruthenium and osmium carbonyl clusters with 1,3,5-triaza-7-phosphatricyclo-[3.3.1.13.7]decane and 3,7-diacetyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane ligands were synthesized using Me3NO as an initiator. The data on antiproliferative activity of new compounds against ovarian carcinoma cell cultures A2780 (cisplatin-sensitive) and A2780cisR (cisplatin-resistant) are reported. The dependence of cytotoxicity on the number of phosphine ligands was demonstrated.
Type
research article
Web of Science ID
WOS:000387600700030
Authors
•
Nosova, Yu. N.
•
Mikhalev, O. V.
•
Kovaleva, O. N.
•
•
Milaeva, E. R.
Publication date
2016
Publisher
Published in
Volume
65
Issue
2
Start page
546
End page
549
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
January 24, 2017
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