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research article

Integrated nanoplasmonic-nanofluidic biosensors with targeted delivery of analytes

Yanik, Ahmet Ali
•
Huang, Min
•
Artar, Alp
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2010
Applied Physics Letters

Performances of the biosensors are often limited by the depletion zones created around the sensing area which impede the effective analyte transport. To overcome this limitation, we propose and demonstrate a nanoplasmonic-nanofluidic sensor enabling targeted delivery of analytes to the sensor surface with dramatic improvements in mass transport efficiency. Our sensing platform is based on extraordinary light transmission effect in suspended plasmonic nanoholes. This scheme allows three-dimensional control of the fluidic flow by connecting separate layers of microfluidic channels through plasmonic/nanofluidic holes. To implement the proposed sensor platform, we also introduce a lift-off free nanofabrication method.

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Type
research article
DOI
10.1063/1.3290633
Author(s)
Yanik, Ahmet Ali
Huang, Min
Artar, Alp
Chang, Tsung-Yao
Altug, Hatice
Date Issued

2010

Published in
Applied Physics Letters
Volume

96

Issue

2

Article Number

article n°021101

Subjects

bioMEMS

•

biosensors

•

microchannel flow

•

nanobiotechnology

•

nanofluidics

•

nanosensors

•

Plasmonics

Editorial or Peer reviewed

REVIEWED

Written at

OTHER

EPFL units
BIOS  
Available on Infoscience
August 16, 2016
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/128661
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