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research article
Chain-Shattering Polymeric Therapeutics with On-Demand Drug-Release Capability
Trigger happy: Trigger-responsive chain-shattering polymeric therapeutics (CSPTs) were prepared by condensation polymerization of a UV- or hydrogen peroxide-responsive domain and a drug as co-monomers. Drug release can be started and stopped by starting and stopping the trigger treatment. Chemotherapeutic-containing CSPTs showed trigger-responsive in vitro and in vivo antitumor efficacy.
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Type
research article
Authors
Publication date
2013
Publisher
Published in
Volume
52
Issue
25
Start page
6435
End page
6439
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
August 15, 2016