Kinetic isotope effects for fast deuterium and proton exchange rates

By monitoring the effect of deuterium decoupling on the decay of transverse N-15 magnetization in D-N-15 spin pairs during multiple-refocusing echo sequences, we have determined fast D-D exchange rates k(D) and compared them with fast H-H exchange rates k(H) in tryptophan to determine the kinetic isotope effect as a function of pH and temperature.


Published in:
Physical Chemistry Chemical Physics, 18, 15, 10144-10151
Year:
2016
Publisher:
Cambridge, Royal Society of Chemistry
ISSN:
1463-9076
Laboratories:




 Record created 2016-07-19, last modified 2018-12-03

n/a:
P404-Canet-Mammoli-Kaderavek-Pelupessy-Bodenhausen-Kinetic-Isotope-Effects-PCCP-18-10144-2016 - Download fulltextPDF
P404a_Communique_Presse_Structure_Dynamique_Biomolecules_Avril_2016 - Download fulltextPDF
Rate this document:

Rate this document:
1
2
3
 
(Not yet reviewed)