A 16-Channel 1.1mm2 Implantable Seizure Control SoC with Sub-μW/Channel Consumption and Closed-Loop Stimulation in 0.18μm CMOS

We present a 16-channel seizure detection system-on-chip (SoC) with 0.92μW/channel power dissipation in a total area of 1.1mm² including a closed-loop neural stimulator. A set of four features are extracted from the spatially filtered neural data to achieve a high detection accuracy at minimal hardware cost. The performance is demonstrated both by early detection and termination of kainic acid-induced seizures in freely moving rats and by offline evaluation on human intracranial EEG (iEEG) data. Our design improves upon previous works by over 40× reduction in power-area product per channel. This improved energy-area efficiency is a key step towards new designs with higher spatiotemporal resolution, larger array size, and therefore, better seizure detection accuracy.

Published in:
Proceedings of the 2016 Symposium on VLSI Circuits
Presented at:
2016 Symposium on VLSI Circuits, Honolulu, Hawaii, USA, June 13-17, 2016
New York, Ieee

 Record created 2016-04-01, last modified 2018-09-13

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