The Red Queen and the persistence of linkage-disequilibrium oscillations in finite and infinite populations

The Red Queen Hypothesis (RQH) suggests that the coevolutionary dynamics of host-parasite systems can generate selection for increased host recombination. Since host-parasite interactions often have a strong genetic basis, recombination between different hosts can increase the fraction of novel and potentially resistant offspring genotypes. A prerequisite for this mechanism is that host-parasite interactions generate persistent oscillations of linkage disequilibria (LD).


Published in:
BMC evolutionary biology, 7, 211
Year:
2007
Publisher:
BioMed Central
ISSN:
1471-2148
Keywords:
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