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The Red Queen and the persistence of linkage-disequilibrium oscillations in finite and infinite populations

Kouyos, Roger D
•
Salathé, Marcel  
•
Bonhoeffer, Sebastian
2007
BMC evolutionary biology

The Red Queen Hypothesis (RQH) suggests that the coevolutionary dynamics of host-parasite systems can generate selection for increased host recombination. Since host-parasite interactions often have a strong genetic basis, recombination between different hosts can increase the fraction of novel and potentially resistant offspring genotypes. A prerequisite for this mechanism is that host-parasite interactions generate persistent oscillations of linkage disequilibria (LD).

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1471-2148-7-211.pdf

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Publisher's Version

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openaccess

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1.83 MB

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Adobe PDF

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7f84f36bf6e0a39a71c9321d24dffafb

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