Inside Job: Viruses Transfer cGAMP between Cells

The DNA sensor, cyclic GMP-AMP synthase (cGAS), is essential for the detection of viral infection. In a recent issue of Science, two studies, Bridgeman et al. (2015) and Gentili et al. (2015), report a novel mechanism for propagating an antiviral signal between cells, based on the transfer of the cGAS enzymatic product, cyclic GMP-AMP (cGAMP), in viral particles.


Published in:
Cell Host & Microbe, 18, 3, 263-265
Year:
2015
Publisher:
Cambridge, Cell Press
ISSN:
1931-3128
Laboratories:




 Record created 2015-12-02, last modified 2018-03-17


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