A series of iridium-stabilized selenocyclohexadienyls of general formula [CpIr((5)-C6H5-nMenSe)][BF4] {Cp = (5)-C5Me5, n = 0, n = 1, and n = 3} is described, with the selenocyclohexadienyl unit being isolated for the first time by -coordination to a CpIr moiety. The solid-state structure of one of [CpIr((5)-C6H2Me3Se)][BF4] was determined by single-crystal X-ray diffraction analysis. These compounds are obtained in good yields as orange-red microcrystalline solids by halogen displacement from the related -bonded arene-chlorinated starting materials using Na2Se as the selenium source. Furthermore, these new compounds display relevant cytotoxic properties towards human ovarian cancer cells.
Type
research article
Web of Science ID
WOS:000356859200028
Authors
Tranchier, Jean-Philippe
•
Dubarle-Offner, Julien
•
Peyroux, Laetitia
•
Gontard, Geoffrey
•
•
•
Amouri, Hani
Publication date
2015
Publisher
Published in
Volume
26
Issue
11
Start page
1563
End page
1566
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
September 28, 2015
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