Fibrinogen fusion proteins, methods of making, and methods of using fibrinogen fusion proteins are described. In a preferred embodiment the fibrinogen fusion protein contains a truncated Aa chain of fibrinogen. The Aa chain contains truncation site, which is a deletion of amino acids at its C-terminal region. A non-fibrinogen protein or peptide is C-terminally attached to the truncation site. The fibrinogen fusion proteins can be used alone or mixed with native fibrinogen to form fibrin polymer.
37192477
Alternative title(s) : (de) Fibrinogenmolekülvarianten-fusionsproteine (fr) Variant moléculaire de protéines hybrides fibrinogènes
TTO:6.0600
Patent number | Country code | Kind code | Date issued |
US2010009409 | US | A1 | 2010-01-14 |
JP2009502166 | JP | A | 2009-01-29 |
EP1913144 | EP | A1 | 2008-04-23 |
WO2007015782 | WO | A1 | 2007-02-08 |