Methods using o<6>-alkylguanine-dna alkyltransferases
A method using O<6>-alkylguanine-DNA alkyltransferases (AGT) is disclosed for transferring a label from a substrate to a fusion protein comprising the AGT. This allows the detection and/or manipulating of the fusion protein, both in vitro and in vivo, by attaching molecules to the fusion proteins that introduce a new physical or chemical property to the fusion protein. Examples of such molecules are, among others, spectroscopic probes or reporter molecules, affinity tags, molecules generating reactive radicals, cross-linkers, ligands mediating protein-protein interactions or molecules suitable for the immobilisation of the fusion protein.
23083030
Alternative title(s) : (de) Verfahren zur verwendung von o6-alkylguanin-dns alkyltransferasen (fr) Procédés d'utilisation de o6-alkylguanine-adn alkyltransférases (en) Methods using o6-alkylguanine-dna alkyltransferases
TTO:6.0310
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